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Loading strategies may need to be altered to accommodate for impaired joint, muscle or tendon function
Overall, in middle-aged mice and men, GLP-1 medicines slightly decrease absolute muscle values but positively impact body composition and mobility.
Because higher doses of GLP-1s commonly cause nausea, bloating, or digestive discomfort, microdosing may make the therapy more tolerable without sacrificing potential benefits
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As cardiologists, obesity is a problem we need to focus on the same way that we focus on BP and lipids and blood glucose and feel comfortable using pharmacological agents as needed
