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The GI side effect profile of the drug itself could mask, mimic, or potentially worsen IBD symptoms, particularly during the dose escalation period when gastrointestinal complaints peak

In addition, the baseline gut microbiome can predict semaglutide treatment effects

Personalized Dosing with Precision Peptide Genetic Testing Your genetic makeup influences how quickly your body metabolizes semaglutide and how well you respond to GLP-1 receptor activation

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The most common side effects are gastrointestinal, including nausea and diarrhoea (affecting more than 1 in 10 people), as well as vomiting, constipation, and abdominal pain

It supports long term collagen and elastic fiber production for progressive tightening