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A large retrospective cohort study of adult female breast cancer patients found that GLP-1 receptor agonist use was associated with better all-cause survival and recurrence-free survival in patients with obesity or type 2 diabetes
In contrast, co-administration of Vutiglabridin overcame this attenuation of efficacy, enabling continuous weight reduction and achieving normal body composition
Mounjaro is the latest GLP-1 to enter the increasingly crowded and complex GLP-1 market, joining Ozempic (indicated for diabetes, 2017) and Wegovy (indicated for weight loss, 2021) among others
Oral GLP-1s and next generation medicines demonstrating higher clinical efficacy or tolerability will likely be positioned to capture premium segments, whereas the bulk of growth in price-sensitive markets like India, China, and Mexico will favour low-cost semaglutide
