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Antibiotic administration can attenuate SGA-induced weight gain, adipose inflammation, and alter lipid metabolism, providing additional evidence for a causal role of the microbiome (69, 70)

These effects often diminish as patients adjust to medication

Several preclinical models and clinical studies also suggest their potential as a novel therapeutic strategy for managing pain symptoms

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This demonstrated that cells pre-treated with Exendin-4 for 18 h responded by an approximate 25% increase in the rate of 2-NBDG uptake, whereas exposure to Exendin-4 for only 30 minutes did not elicit any significant change (Fig

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