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The hypothalamus is the main regulator of the energy balance in the body

doi: 10.3390/biomedicines13020359

The STEP-1 and STEP-2 trials showed that once-weekly semaglutide reduced body weight by 14.9% and 9.6% in non-diabetic and diabetic obese patients, respectively [40,49]

Although numerous animal studies have revealed the mechanism of mushroom polysaccharides on disease through the regulation of gut microbiota, further validation and exploration of its potential mechanisms are needed through metabolomics and metagenomics methods and higher-quality clinical trials

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