is tirzepatide a glp 1 drug GLP-1 Medications for Weight Loss: Semaglutide vs vs Retat – Revolution Health & Wellness Study flags need to monitor

Patent number: US10278961B2, CN108997332B, US20230138576A1

An update on peptide-based therapies for type 2 diabetes and obesity

GLP-1 RAs help by: Decreasing pro-inflammatory cytokine levels Reducing the Psoriasis Area Severity Index (PASI) Improving insulin sensitivity and reducing obesity (both of which exacerbate psoriasis) Wound Healing: In diabetic patients and others with chronic wounds, GLP-1 medications improve healing by: Reducing harmful MMP-9 levels and improving MMP-9/TIMP ratios Enhancing angiogenesis (new blood vessel formation) Normalizing C-reactive protein (CRP) levels, a marker of systemic inflammation Multi-System Anti-Inflammatory Effects of GLP-1 Medications GLP-1 agonists exhibit systemic anti-inflammatory effects across multiple organ systems: Cardiovascular: Reduces arterial plaque, improves endothelial function Renal: Protects glomeruli, reduces proteinuria, slows kidney disease progression Pulmonary: Reduces airway inflammation, potential benefits in asthma and COPD Liver (NAFLD/NASH): Lowers hepatic inflammation, improves liver enzymes GI/Metabolic: Reduces markers like IL-6 and CRP

These strategies work best as part of a comprehensive health approach

Available from: Vosburg RW, El Chaar M, El Djouzi S, Docimo S, Choi D, LaMasters T et al (2022) Literature review on antiobesity medication use for metabolic and bariatric surgery patients from the american society for metabolic and bariatric surgery clinical issues committee

Both oral GLP-1 drugs and GLP-1 injections are highly effective for controlling blood sugar and aiding weight loss