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Unlike the current widely used medications such as Ozempic and Mounjaro that target the GLP-1 pathway alone, retatrutide, known as a GLP-3, targets three pathways related to metabolism: GIP, GLP-1, and glucagon

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In two peer-reviewed clinical trials a 12-week study and a 6-month replication study participants taking 400mg of Morosil daily showed measurable improvements in body composition markers compared to placebo, including BMI, and waist and hip circumference

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Professor Giles Yeo joins this Journal Club session to discuss a recently published clinical trial paper exploring the effects of the weight loss drug, semaglutide.

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