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Factors such as side effects, high out-of-pocket costs, injection fatigue and stigma around obesity treatment drive troves of patients some studies estimate roughly half or more to stop GLP-1s within a year and risk regaining the weight they lost
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The net effect is that after MBS, endogenous GLP-1 primarily acts on the brain to inhibit appetite, while only 10% of the secreted GLP-1 reaches the pancreas

Anti-obesity drug sales led both long- and short-term growth among the top ten retail therapies by sales in terms of 2019-2024 5 year compound annual growth

Les analogues du GLP-1 sont des mdicaments de plus en plus utiliss dans la gestion de l'obsit et du diabte de type 2