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In conclusion, the paper provides evidence that the reduction of GLP-1+ cells is a general feature of ileal and colonic inflammation in mice and humans and is likely due to altered epithelial differentiation driven by changes in cellular metabolism, particularly mitochondrial dysfunction.

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Tirzepatide is designed as a once-weekly injection based on clinical trial design and pharmacokinetics

PlexusDx explains GLP-1 safety after cholecystectomy and personalized treatment options

The Food and Drug Administration on Friday approved Eli Lillys weight-loss drug Zepbound to treat sleep apnea, a common but potentially serious sleep-related breathing disorder, marking it the first medication for certain patients with the condition.