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IL-33 potentiates a type 2 allergic inflammatory response, activating immune cells including ILC2s, Th2 cells, mast cells, and basophils [12,13]
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The most recent Phase 3 trial showed discontinuation rates of 12-18% due to adverse events, higher than existing GLP-1 medications
[DOI] [PubMed] [Google Scholar] 84.Linge J, et al
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