glp-1 weight loss research Genetic predictors for efficacy and side effects identified Weight Reduction with GLP-1 Agonists

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GLP-1 drugs shown cost-effective for knee osteoarthritis and obesity A new study led by investigators at Mass General Brigham finds that adding novel weight loss GLP-1 drugs semaglutide and tirzepatide to usual care represents a cost-effective treatment strategy for people with knee osteoarthritis and obesity, with tirzepatide providing greater health benefits at lower cost compared to semaglutide

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Patients with type 2 diabetes who are prescribed liraglutide have a 179% higher likelihood of developing non-arteritic anterior ischemic optic neuropathy (NAION), while those prescribed insulin have an 86% greater likelihood compared to patients who were prescribed other diabetes medications