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Increase fiber intake gradually, aiming for 25 to 30 grams daily

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Gault VA, Kerr BD, Harriott P, Flatt PR (2011) Administration of an acylated GLP-1 and GIP preparation provides added beneficial glucose-lowering and insulinotropic actions over single incretins in mice with type 2 diabetes and obesity

The receptor binding affinity and potency of the cyclic and linear peptides were compared, and the results clearly suggest the presence of two helical segments (residues 1121 and 2334) in the N- and C-terminal regions of the receptor-bound conformation