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Chang et al., 2015
Importantly, although RETA-w/d restored the tumor transcriptome close to that of Veh, the tumor progression remained relatively blunted, which could be due to factors external to the tumor including systemic metabolic effects, such as insulin concentration, which were only partially restored after RETA-w/d, as discussed above
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That is, people with obesity have a higher risk of developing depression, and people with depression are also more likely to have excess weight
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