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Semaglutide, a selective GLP-1 receptor agonist marketed as Ozempic, Wegovy, and Rybelsus, is one of the most extensively studied anti-obesity and anti-diabetes medications in history, with over 25,000 clinical trial participants and FDA approval for three distinct indications

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Upon completion of each trial, the water was replaced before proceeding with the subsequent test

Incretin Treatment and Risk of Pancreatitis in Patients With Type 2 Diabetes Mellitus: Systematic Review and Meta-Analysis of Randomised and Non-Randomised Studies

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As obesity is a complex, chronic and progressive disease, it requires also an individualised and adaptive over time approach [14, 102]