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43.Lamperti M, Romero CS, Guarracino F, Cammarota G, Vetrugno L, Tufegdzic B et al (2025) Preoperative assessment of adults undergoing elective noncardiac surgery: Updated guidelines from the European Society of Anaesthesiology and Intensive Care

Unlike sustained receptor agonism by GLP-1R agonists (6, 22, 23), the novel dual agonist I-M-150847 induces unique spatiotemporal incretin receptor signaling that promotes cAMP generation at the plasma membrane promoting glucose-stimulated insulin exocytosis

In a meta-analysis with patients with T1D, weight loss with liraglutide 1.8 mg was estimated at ~5 kg compared to placebo (62), and there was a dose-response effect

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