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Due to potential risks of medullary thyroid carcinoma and multiple endocrine neoplasia, its not recommended for individuals with a personal or family history of these conditions [45]

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doi: 10.1016/j.ejca.2015.09.027 [DOI] [PubMed] [Google Scholar] 51.Nayan M, Punjani N, Juurlink DN, et al

Chew thoroughly and pace meals (2030 minutes)

The initial twice-daily formulation was discontinued due to exceptionally high rates of gastrointestinal adverse events (nausea and vomiting), leading to discontinuation rates exceeding 50% in trials