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Clinical studies reporting variability in lean mass trajectories and dietary intake during GLP-1RAassociated weight loss [40, 75] suggest that adaptive stability may depend not only on receptor-mediated signaling but also on substrate availability during sustained hypophagia

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However, it is impractical to keep patients on the same diet longitudinally, especially because GLP-based therapies alter appetite and food intake

While including small servings of ice cream as part of a balanced, nutritious diet is not dangerous, decisions about types and brands require careful consideration