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Despite some minor deviations in aggregate baseline characteristics, including sex, percentage of participants that were Hispanic and percentage of participants with prediabetes at baseline, the study populations were deemed to be sufficiently comparable in terms of treatment effect modifiers (Table 1)

For a 250-pound individual, that could mean losing 37 to 62 pounds

Swainson MG, Batterham AM, Tsakirides C, Rutherford ZH, Hind K

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Watch Your Portions Even healthy foods can cause problems if you eat too much at once