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Risk of bias tools - ROBINS-I V2 tool Accessed 16 Aug 2025 Schnemann HJ, Brennan S, Akl EA et al (2023) The development methods of official GRADE articles and requirements for claiming the use of GRADE - a statement by the GRADE guidance group

Long acting formulations requiring monthly or less frequent dosing could further improve adherence

The most common side effects from taking Semaglutide and Tirzepatide include, but are not limited to: Nausea, vomiting, diarrhea, constipation, abdominal pain, headache, fatigue, dyspepsia, dizziness, hypotension, abdominal distension (bloating), eructation (burping), hypoglycemia in patients with type 2 diabetes, flatulence (gas), gastroenteritis, gastroesophageal reflux disease, injection site reactions, allergic reactions, and hair loss

If you experience persistent nausea, inform both your endocrinologist and prescribing physician

D., & Williams, J
