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Evento moderato (sintomatologia persistente e disturbante): valutare una riduzione temporanea della dose, con tentativo di rientro alla dose target dopo risoluzione

The metabolic profile of these mice shifted towards an increase in glycolysis and a significant decrease in fatty acid oxidative phosphorylation

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Clinically meaningful response usually begins at 1.0 mg or higher

When asked about potential negative impacts on developing adolescents, there was no hesitation from lead study author Daniel Weghuber, M.D., from the Department of Pediatrics at Paracelsus Medical University in Salzburg, Austria