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I also question the comparison of GLP-1 weight loss medications to non-GLP-1 weight loss medications because most of the medications in non-GLP-1 classes work to alter brain chemistry and would be much more likely to induce new or worsening symptoms of anxiety and depression

[DOI] [PubMed] [Google Scholar] 49.Tomlinson B, Hu M, Zhang Y, Chan P, Liu ZM

Heart failure and fluid buildup

Some with no prior gastrointestinal disease developed apparently permanent dysfunction

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In pharmacovigilance databases, anxiety comprised 38.7% of psychiatric adverse event reports, but psychiatric reports as a whole represented only 1.18% of total adverse event reports for GLP-1 receptor agonists