what happens when you go off a glp 1 Something Grim Is Happening to People Who GLP-1s Two Years After Stopping GLP-1s,

Distribution of glucagonlike peptide I (GLPI), glucagon, and glicentin in the rat brain: An immunocytochemical study

Testing the effects of the GLP-1 receptor agonist Exenatide on cocaine self-administration and subjective responses in humans with cocaine use disorder

Genes (Basel) (2019) 10(10):798

with focus on glucagon-like peptide-1

These findings were confirmed in high-fat, high-cholesterol (HFHC) dietfed mice with functional LDL receptor deficiency induced by viral expression of proprotein convertase subtilisin/kexin type 9adeno-associated virus (PCSK9-AAV), in which daily administration of semaglutide for 18 weeks reduced aortic plaque area (11)

GLP-1 medications are engineered versions of this hormone designed to last much longer in the body (anywhere from a day to a week per dose), which is why they are commonly taken as a once-weekly injection