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2021;53 doi: 10.1016/j.molmet.2021.101296
No direct equivalency exists because tirzepatide engages both GLP-1 and GIP pathways, while semaglutide only activates GLP-1 receptors
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If you have been on an adequate dose for 12 or more weeks and have experienced virtually no weight loss from the beginning , that may indicate a genuine non-response
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