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2024;9:234 Rosenstock J, Sorli CH, Trautmann ME, Morales C, Wendisch U, Dailey G, et al

The compound was significantly less potent at rGLP-1R, and this species difference enabled the identification of Trp 33 (Ser 33 in rGLP-1R) as being the critical residue

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However, individual responses vary

Universit de Louvain researchers found that fiber fermentation in the lower intestine creates short-chain fatty acids (SCFAs) that trigger GLP-1 secretion (PMID: 33820962)

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