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There are also many multi-target dual agonists under development, such as GLP-1R/GCGR, GLP-1R/fibroblast growth factor 21 receptor (FGF21R), etc

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The American Society for the study of liver diseases advises against the use of vitamin E in individuals with compensated liver cirrhosis and DM although studies that demonstrated the benefits of vitamin E treatment did include these patients

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