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Roux-en-Y gastric bypass and calorie restriction induce comparable time-dependent effects on thyroid hormone function tests in obese female subjects

This can result in either a stronger initial hit, as the outer coating or time release is more broken down, or in a weaker effect, as more of the medication is simply destroyed by stomach acid

100.Gupta L, Khandelwal D, Kalra S, et al

Patients have lost an average of 12.4% body weight on this medication

Adverse events, most commonly gastrointestinal disorders, led to discontinuation for 6.7% in the semaglutide group and 3% in the placebo group, according to the researchers

Here are four key players: Soluble fiber deserves special attention