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Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially developed for the treatment of type 2 diabetes and obesity, may modulate pathways associated with the hallmarks of aging

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In these Ghsr+Glp1r+ neurons, ghrelin preadministration abolished the GLP-1-induced calcium response

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Learn their history, when they were introduced, and why these medications are widely used today.