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Slow gastric emptying and reducing hunger

People with kidney disease, older adults, and those using diuretics or blood pressure medicines may need earlier clinical review if fluid losses occur

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Mice without a functional GPR40 display an impaired CCK and GLP-1 secretion after an oil gavage, while surprisingly animals deficient for GPR120 display a normal corn oil-induced GLP-1 secretion (80, 262)

tirzepatide works on a second hormone pathway as well, and some patients respond to it better

However, this research was limited in that it included mostly white participants, which is not fully representative of the diverse population of people with type 2 diabetes in the US