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Harnessing glucagon-like peptide-1 receptor agonists for the pharmacological treatment of overweight and obesity

Originally developed for managing blood glucose levels in people with type 2 diabetes, GLP-1 receptor agonists like Ozempic have demonstrated impressive results in supporting healthy weight loss

With weight loss, there is also loss of fat-free mass, which raises concern for the development of sarcopenia

With the exception of the oral formulation of semaglutide, GLP-1RAs have to be injected subcutaneously daily or once weekly (33, 34, 36)

[DOI] [PubMed] [Google Scholar] 87.Terami N., Ogawa D., Tachibana H., Hatanaka T., Wada J., Nakatsuka A., Eguchi J., Horiguchi C.S., Nishii N., Yamada H., et al

Novo did not reveal the agreed-upon price, but said it will have a low-single digit impact on sales