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SGLT2i: 0.88[0.82-0.95]), and renal composite outcome (GLP1RA: 0.86[0.78-0.94)

12 Another possibility may be uncertainties related to GLP-1 RA administration increasing heart rate and the latter having been associated with cardiovascular mortality

Regular monitoring is essential to assess treatment efficacy and adjust therapy as needed

The study concluded that once-weekly doses of tirzepatide provided substantial and sustained reductions in body weight over the 72-week period

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10.1016/S0140-6736(18)32261-X
