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Keywords: obesity, leptin resistance, partial leptin reduction, weight loss, treatment strategies Introduction The prevalence of obesity and associated diseases has been obviously increasing in recent years, and there are growing interests in the pathogenesis of obesity and the development of anti-obesity drugs

Sarcopenia Sarcopenia is the clinical term for age-related or disease-related muscle loss , but in the context of rapid weight loss, it describes the breakdown of muscle tissue for energy

Also, in a 40-week trial comparing tirzepatide to semaglutide in individuals with type 2 diabetes, those on tirzepatide lost more weight

Typically speaking, patients can expect to start to visibly lose weight while on Ozempic after several weeks

The common side effects of semaglutide include: These side effects usually decrease over time as the body adjusts to the medication

Curr Atheroscler Rep (2004) 6(3):1805
