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Furthermore, GLP-1 and glucose-dependent insulinotropic polypeptides have been shown to induce substance P release from sensory nerves expressing TRPV1 and TRPA1, broadening the potential pain modulation mechanisms of GLP-1 and suggesting their application in peripheral pain management 64

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The actual amounts were 29% to 39% higher than labeled, meaning people could be taking much more of the drug than they intended to take which poses serious health risks

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