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[1] [2] Patients with a history of diabetic retinopathy require careful consideration, as the SUSTAIN-6 trial identified a higher incidence of retinopathy complications in the semaglutide group, particularly in those with pre-existing retinopathy and rapid improvement in blood glucose control

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Yes, thigh injections deliver semaglutide into subcutaneous tissue with identical absorption and effectiveness as abdominal injections