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Managing Side Effects During Dose Escalation Nausea, constipation, and loss of appetite are the most commonly reported side effects, particularly in the first few weeks after a dose increase

If an NSAID doesnt provide enough relief, or if side effects become problematic, your doctor may prescribe a drug belonging to a category called tumor necrosis factor (TNF) alpha-blockers

The thiazolidinedione class of glucose-lowering agents, exemplified by pioglitazone and rosiglitazone, exerts pleiotropic anti-inflammatory effects in multiple peripheral tissues, including the cardiovascular system [9]