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doi: 10.1007/s40259-013-0057-y

They had a product that was expensive, under huge demand and then in shortage

From a pharmacological perspective , Ozempic does not truly "wear off" during the week when used as prescribed
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Although GLP-1 medications have complex dosing schedules, you can consider switching between GLP-1 medications if you experience intolerable side effects with your current medication, do not get significant results, or due to a drug shortage

This can affect their therapeutic effectiveness

Tirzepatide was removed from the FDA shortage list in late 2024
