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doi: 10.1007/s40262-018-0728-4 [DOI] [PubMed] [Google Scholar] 35

Naltrexone was originally developed to treat opioid and alcohol dependence
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Addresses the Root Causes of Weight Gain One major limitation of traditional dieting is that it often ignores the biological factors that make weight loss so difficult

One of the principal concerns surrounding engineered probiotics is the potential for horizontal gene transfer, including the dissemination of GLP-1 expression cassettes or their regulatory elements into wild-type microbial populations
