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This effect is part of the entero-insular axis of glucose homeostasis and is estimated to be responsible for at least 50% of insulin secretion [2, 3]

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After one month of the hormone treatment, GE2-treated subjects of both sexes lost significantly more weight their vehicle-treated counterparts (Treatment and diet interaction: F( 1,47 ) = 9.936, p 2 = 0.175, p = 0.003

We quantified differences in (1) likelihood of achieving 5% or greater, 10% or greater, and 15% or greater weight loss, and (2) percentage change in body weight at 3, 6, and 12 months with treatment

Cranston, A

Elabd, Warda Othman Egyptian Liver Journal.2026;[Epub] CrossRef Possible correlations between infertility and adverse metabolic profile: a case-control study Carmen Imma Aquino, Nicole Vercellino, Elisabetta Fortina, Daniela Ferrante, Cristina Rigamonti, Rosalba Minisini, Mario Pirisi, Valentino Remorgida, Mattia Bellan, Daniela Surico European Journal of Obstetrics & Gynecology and Reproductive Biology.2026