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You suspect you may have an underlying condition that makes it difficult to lose weight

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GLP-1 drugs slow stomach emptying, which can leave food or liquid in your stomach during surgery

Learn more about Tirzepatide There are many potential reasons why switching from semaglutide to tirzepatide might be beneficial

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Alternative pharmacological options with established safety profiles include: Semaglutide (Wegovy): Another GLP-1 receptor agonist with robust weight loss data and cardiovascular risk factor improvements (with cardiovascular outcome benefits demonstrated in the SELECT trial) Liraglutide (Saxenda): Daily GLP-1 agonist injection licensed for weight management Orlistat: Lipase inhibitor that reduces dietary fat absorption, available over-the-counter or on prescription Each has distinct side effect profiles and may suit different patient populations