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A meta-analysis involving more than 70,000 participants with type 2 diabetes (SMART-C) found that the cardiovascular benefits of SGLT-2 inhibitors, including reductions in MACE, cardiovascular death, hospitalisation for HF, and CKD progression, were consistent regardless of whether patients were receiving a GLP-1 receptor agonist at baseline [19]

The Role of Glucagon-like Peptide 1 (GLP-1) in Addictive Disorders

The safety monitoring committees, whose entire job is to flag concerning side effect patterns, did not raise urinary tract infections as a signal worth investigating further

That arbitrage doesnt exist in Canada, because the generic is already going to be so cheap, so theres nothing for a compounder to undercut

Tirzepatide (Mounjaro), the dual GIP/GLP-1 receptor agonist, is licensed by the MHRA for the treatment of type 2 diabetes