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105 Other potential combinations include GLP-1 RAs with SGLT-2 inhibitors, 106 amylin analogs, or central nervous system appetite modulators, such as phentermine or bupropion

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However, some health insurance companies are starting to expand their coverage for GLP-1s

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Tirzepatide, like semaglutide, is a large peptide unlikely to transfer significantly into breast milk based on theoretical pharmacokinetic properties, but formal lactation studies have not been conducted

In addition, there is no guarantee it will translate to positive fund performance