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First-generation antihistamines like Benadryl and Chlor-Trimeton may be used but can cause drowsiness

[DOI] [PMC free article] [PubMed] [Google Scholar] 313.Foreman R.E., Bannon C.A., Kay R.G., Reimann F., Gribble F.M

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While not a direct side effect of Mounjaro, its overall effect could contribute to conditions that trigger eye twitching
