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GLP-1 medications do reduce appetite, but they also slow stomach emptying, improve fullness signaling, and help regulate blood sugar by affecting insulin and glucagon pathways

Blonde L, Jendle J, Gross J, Woo V, Jiang H, Fahrbach JL, et al

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One seen as easier: GLP-1 medications

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Reach out to your healthcare provider if fatigue feels severe, keeps getting worse, or sticks around after the initial adjustment period