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GLP-1s can cost up to $1,000 or more each month before insurance, savings cards, or other discounts

Berberine Best for: Someone with mild insulin resistance or prediabetes, or someone who struggles to tolerate high-dose pharmaceuticals

NCT03548935, NCT03552757, and NCT03611582, clinicaltrials.gov This article contains supplementary material online at References 1

Implications for employers: This study is consistent with other studies of GLP-1 medications for both diabetes and obesity demonstrating substantial cardiovascular and metabolic benefits of this class of medications

10.1371/journal.ppat.1007581 27 FoleyS
