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In head-to-head comparisons of SGLT-2 inhibitors versus GLP-1 receptor agonists, we only observed small differences (hazard ratio 0.92 in the primary analysis), and in several secondary and sensitivity analyses we observed no association

Researchers can use GLP-1 receptor agonists, which have received diabetes treatment approval, to develop arthritis therapies because this approach will shorten both the time needed for drug development and the expenses involved