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We further proposed that GLP-1R-mediated delivery of tesaglitazar would provide beneficial glucometabolic effects at doses subthreshold for each monotherapy, thereby improving systemic metabolism at more tolerable doses

Reductions in A1c levels were similar in any duration of diabetes in DUAL-1 and 2

Castillo-Rodriguez E, Fernandez-Prado R, Esteras R et al

If symptoms persist, consult a healthcare provider for anti-nausea medication (e.g

(2) I (Intervention): GLP-1 RAs as a whole or as a single drug

(2012) The once-weekly human GLP1 analogue semaglutide provides significant reductions in HbA1c and body weight in patients with type 2 diabetes