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The differences within the GLP-1 class are significant enough to affect clinical decision-making

Semaglutide, for example, can reduce HbA1c by up to 1.8% and weight by up to 6.5 kg

For renal impairment, although most GLP-1 agents have minimal renal clearance, impaired kidney function increases the risk of adverse events such as dehydration from vomiting or decreased drug clearance in polypharmacy

Even so, the findings provide clarity for patients and clinicians navigating a rapidly evolving area of care

Managing Side Effects Managing Side Effects Like any medication, GLP-1 weight loss injections can cause side effects

As soon as one of the drugs came on the market - Wegovy launched here on July 1 last year - you got a prescription and forked out close to $500 a month over eight months