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PlexusDx uses the Precision Peptide Genetic Test to identify whether your GLP1R and GIPR genes predict strong medication sensitivity, helping your doctor choose your starting point strategically

Oncotarget 7 , 5081450815 (2016)

The dosing schedule of Wegovy is as follows: Starting dose: 0.25 mg once weekly for the first 4 weeks Titration phase: 0.5 mg once weekly for the next 4 weeks and then, if tolerated, 1 mg weekly for the next 4 weeks Maintenance dose for long-term weight management: If further weight management is needed, your prescriber will increase the dosage to 1.7 mg once weekly for the next 4 weeks Maximum dose: 2.4 mg once weekly Efficacy A clinical study shows that Wegovy (2.4 mg once weekly) decreased 10-15% of body weight compared to 2-3% with placebo

Wegovy highlights of prescribing information, Novo Nordisk (2024) The risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon-like peptide-1 receptor agonist therapy, Scientific Reports (2024) Decreased risk of anxiety in diabetic patients receiving glucagon-like peptide-1 receptor agonist: A nationwide, population-based cohort study, Frontiers in Pharmacology (2022) Most GLP-1 medications correlated with a lower likelihood of anxiety and depression diagnoses, Epic Research (2024) Dopamine release in the midbrain promotes anxiety, Biological Psychology (2021) Dopamine primes the brain for enhanced vigilance, MIT News (2018) Why your cardiologist may prescribe semaglutide (Wegovy), Yale Medicine (2024) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice

However, understanding your individual peptide-pathway genetics helps optimize semaglutide dosing, which indirectly affects how your stomach processes all medications, including antibiotics