glp 1/gip vs glp 1 Targeting GLP-1, GIP & GCG in Obesity and Type 2 Diabetes Research New strategies for the treatment

Common neural targets for obesity treatment Emerging evidence suggests that both GLP-1RAs and physical exercise converge on common neural pathways, influencing brain regions involved in appetite regulation, energy balance, and cognitive function

Dulaglutide (Trulicity) begins at 0.75 mg once weekly, with potential increases to 1.5 mg, 3 mg, or a maximum of 4.5 mg weekly based on glycemic response

In individuals with non-alcoholic fatty liver disease, low doses of Semaglutide (0.10.4 mg) administered over 72 weeks is associated with enhanced physical function and increased energy levels, as reported through standardized self-assessments What the evidence suggests: Low-dose Semaglutide may improve physical function, emotional wellness, and overall quality of life

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Real-world data from a Truveta study of over 18,000 patients found that tirzepatide users achieved greater weight loss at 12 months compared to semaglutide users, consistent with the SURMOUNT-5 findings [4]