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Conversely, a single-institution study of 1,191 participants failed to find a difference in the rate of new retinopathy or existing retinopathy progression between GLP-1/GIP agonist or SGLT2 inhibitors when the amount of hemoglobin A1c reduction was the same in the two treatment arms

By combining the two drugs, researchers were hoping to preserve muscle mass during weight loss

The findings so far suggest both remarkable promise and significant limitations

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Certain conditions may preclude use of tirzepatide

They serve as an adjunct tool to support continued appetite control and metabolic health in the long term