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Persistent fatigue Emotional stress Increased appetite Compromised mobility Low mood/anxiety Difficulty with weight regulation Low self-esteem Sleep disturbances **Average weight-loss results cited (21% for tirzepatide and 1516% for semaglutide) are based on peer-reviewed clinical trials published in leading medical journals, including The New England Journal of Medicine

Significant weight has been lost, reducing the physical burden of daily movement

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So if you stop this medication two months ahead of time, then it takes you three months to get pregnant, now youve been off of it for five monthsand most people are going to regain some of the weight in that timeframe, says Dr